Applications of ManNAc
The application of N-acetylmannosamine to the mammalian cell culture production of recombinant human glycoproteins
Selwyn C Yorke
Keywords: N-acetylmannosamine, sialylation, glycoproteins.
This mini-review covers recent developments in the understanding, role and value of N-acetylmannosamine (ManNAc) as a compound that can improve sialylation during the production of recombinant human glycoproteins.