Structural Formula

Deoxycholic Acid

Formula

C24H40O4

Deoxycholic Acid

Description

Deoxycholic acid and its sodium salt are manufactured at NZP in large volumes. In nature, deoxycholic acid, which is referred to as a "secondary bile acid", is produced in the intestine from the salts of glycocholic and taurocholic acid (see cholic acid ) by the action of bacterial enzymes. Less than half of the deoxycholic acid is absorbed by the intestine and is returned the liver where it is conjugated and released into the gall bladder.

Deoxycholic acid is extracted from bovine bile, (also known as "cattle bile" or "ox bile") which is a by-product of the meat processing industry.

It is also available as the water soluble sodium salt.

Use of Chemical

Historically deoxycholic acid was used as an intermediate for the production of corticosteroids, which have anti-inflammatory indications. An emerging use of deoxycholic acid is as a biological detergent to lyse cells and solubilise cellular and membrane components.

Specifications

  • CAS Number: 83-44-3
  • Molecular Weight: 392
  • Solubility: Sparingly soluble in water-soluble in alcohol and to a lesser extent acetone and glacial acetic acid.
  • Packaging: Deoxycholic is sealed in a polyethylene liner and packed in 25kg fibre drums. Customer specific packaging can be provided.