Structural Formula

D-Mannosamine hydrochloride

Formula

C6H13NO5.HCl

D-Mannosamine hydrochloride

Description

D-mannosamine (2-Amino-2-deoxy-D-mannose) is a monosaccharide involved in a range of metabolic processes. In its N-acetyl form it is a constituent of neuraminic acids, glycolipids and glycoproteins.
 
D-Mannosamine hydrochloride is an important monosaccharide starting material for a range of important biologically functional derivatives; especially N-acylmannosamines and bioactive butyl esters.

Use of Chemical

D-mannosamine hydrochloride is used for the synthesis of sialic (N-acetylneuraminic) acid derivatives. It is also a synthetic intermediate for a number of carbohydrate-derived families of biologically active compounds and pharmaceutical candidates.
 
D-mannosamine hydrochloride is the preferred synthetic precursor of N-propanoyl mannosamine and other N-acyl precursors of sialic acid (N-acyl neuraminic acids).

Specifications

  • CAS Number: 5505-63-5
  • Molecular Weight: 215.6
  • Solubility: Water soluble
  • Packaging: D-mannonsamine hydrochloride is sealed and shipped in two polyethylene liners and packed in 20 kg fibre drums. Customer specific packaging can be provided. Quantities from 100 g are available for sale. Store refrigerated.

Relevant Publications

Werner A, Horstkorte R, Glanz D, Biskup K, Blanchard V, Berger M, Bork K."Glycoengineering the N-acyl side chain of sialic acid of human erythropoietin affects its resistance to sialidase". Biol Chem. 2012 Aug;393(8):777-83. doi: 10.1515/hsz-2012-0138.